Courses 1st Semester
- Molecular and Clinical Bacteriology
- Molecular and Clinical Virology
- Mycology and Parasitology
- Immunology of Infectious Diseases and Vaccines
- Pathogenetic mechanisms and Genetic variability
- Pathogenetic mechanisms and metabolism
- Good Laboratory Practice, Biosafety and Bioethics
- Laboratory Courses I
ECTS 6
Coordinators
Assoc. Prof. Maria Panopoulou
Prof. Ioannis Kourkoutas
Course Layout
Section I (4h)
- Introduction to Bacteriology
- Bacterial genetics
- Pathophysiology of bacterial infections
Section II (4h)
- Mycobacterium tuberculosis
- Non-tuberculosis mycobacteria
- Brucella spp
Section III (4h)
- Enterobacteriaceae
- Campylobacter spp
- Vibrios
- Helicobacter pylori
Section IV (4h)
- Bacillus anthracis
- Clostridium spp
- Corynebacterium diptheriae
- Spirochaetales
Section V (4h)
- Rickettsia
- Chlamydia
- Human microbiome
ECTS 6
Coordinators
Prof. Katerina Chlichlia
Assoc. Prof. Ioannis Karakasiliotis
Course Layout
SECTION I (2h)
- Introduction to Virology
(General concepts on: What is a virus?/life cycle/genetics and genomics/emerging and re emerging viruses/ oncogenic viruses/ vector borne viruses)
SECTION II (4h)
Positive strand RNA viruses
- Picornaviruses : Polio and other viruses
- Flaviviruses: HCV and other viruses
- Coronaviruses: SARS and other viruses
- Hepaciviruses: HCV
SECTION III (5h)
Negative strand RNA viruses
- Orthomyxoviruses: Influenza
- Paramyxoviruses : Measles , Rubella
- Filoviruses: Ebola
- Rhabdoviruses: Rabies
SECTION IV (5h)
DNA viruses
- Papillomaviruses
- Polyomaviruses
- Herpesviruses : HSV1/2, VZV, CMV, EBV, Kaposi Sarcoma
- Poxviruses : Vaccinia
- Adenoviruses
SECTION V (2h)
- Retroviruses: HTVL I/II , HIV
SECTION VI (2h)
- Hepadnaviruses: HBV
SECTION VII (2h)
- Viral vectors in Gene Therapy
ECTS 5
Coordinators
Prof. Anastasia Diakou
Assoc. Prof. Maria Panopoulou
Course Layout
SECTION I (4h)
- Molecular and Clinical Parasitology (Part 1)
- Biology and life cycle of human parasites, Pathophysiology of parasitic infections, Intestinal and urogenital protozoa
- Εntamoeba histolytica
- Giardia lamblia, Dientamoeba fragilis, Trichomonas vaginalis
- Balantidium coli
- Ιsospora belli, Sarcocystis, Cryptosporidium, Cyclospora
SECTION II (2h)
- Molecular and Clinical Parasitology (Part 2)
- Blood and tissue parasites, Arthropods
- Plasmodium spp, Leishmania, Τrypanosoma, Τοxoplasma, Babesia
- Arthropoda
SECTION III (4h)
- Molecular and Clinical Parasitology (Part 3)
- Helminths: Nematodes,Trematodes, Cestodes
- Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichinella spiralis
- Schistosoma
- Taenia, Echinicoccus
SECTION IV (4h)
- Molecular and Clinical Mycology (Part 1)
- Fungal classification, structure and morphology
- pathogenicity and pathogenesis of fungal infections
- Superficial fungal infections
SECTION V (4h)
- Molecular and Clinical Mycology (Part 2)
- Systemic fungal infections
- Endemic dimorphic fungi
ECTS 5
Coordinators
Prof. Katerina Chlichlia
Assoc. Prof. Aglaia Pappa
Course Layout
SECTION I (4h)
Introduction to Immunology
- Innate immunity to pathogens
- Adaptive immunity to pathogens (Humoral and Cell-mediated immune responses)
SECTION II (4h)
Immune responses to pathogenic microorganisms
- Immune responses to intracellular and extracellular bacteria (Staphylococcus, Mycobacteria etc.)
- Immune responses to viruses (Influenza, Polio, Measles, HIV, HSV, HPV)
- Immune responses to parasites and fungi (Trypanosoma, Leishmania, Schistosoma, Plasmodium, Candida)
SECTION III (2h)
- Pathogen-induced evasion of protective immune responses.
SECTION IV (2h)
- Microbiome, microbiota and host immune system.
SECTION V (4h)
Immunization – Vaccines
- Active Immunization, types of Vaccines, Adjuvants
- Design of new generation vaccines
ECTS 3
Coordinators
Assoc. Prof. Aglaia Pappa
Asst. Prof. Marianthi Georgitsi
Course Layout
SECTION I (2h)
- Introduction to Polymorphisms in Host Genetics
- Prognostic significance of host gene polymorphisms
SECTION II (2h)
- Lost genetic polymorphisms and therapy outcome
- Host genetic polymorphisms and desease severity
SECTION III (2h)
- Inheritabe immunity to infectious diseases
SECTION IV (2h)
- Impact of host genetic polymorphisms on vaccine induced antibody response
- Genetic Polymorphisms in Host Innate Immune Sensor Genes
ECTS 2
Coordinators
Prof. Ioannis Tentes
Asst. Prof. Katerina Katsani
Course Layout
SECTION I (2h)
Introduction to common host metabolic processes targeted by pathogens
- Main metabolic pathways (carbohydrate, lipid, protein) – energy metabolism
- Control mechanisms of host metabolism (substrates, intermediates, enzymes).
- Tissue/organ metabolic priorities and energy resources usage maintaining blood glucose homeostasis
SECTION II (2h)
How the host’s metabolic priorities are diverted as a result of pathogenic invasion
- The paradigm of bacterial infection
- The paradigm of Hepatitis C virus
- The paradigm of parasitic infection.
SECTION III (2h)
Nutrition and infection.
- Iron metabolism and infection.
- Μalnutrition and inflammation.
SECTION IV (2h)
Oncogenic viruses and metabolism.
- The common pathways of energy usage in viral infection and cancer.
- Oxidative stress, apoptosis and extreme metabolic scenarios.
ECTS 2
Coordinators
Prof. Katerina Chlichlia
Assoc. Prof. Ioannis Karakasiliotis
Course Layout
SECTION I (2h)
- Good Laboratory Practice and Good Manufacture Practice – strategies in managing health and safety
SECTION II (2h)
- Biosafety: Biologic agents – Biosafety Levels – Risk assessment
SECTION III (2h)
- Biosafety: Safety in working with bacteria and viruses
SECTION IV (2h)
- Biosafety: Safety in working with laboratory animals
Laboratory Courses
Coordinators
Prof. Konstantinos Mimidis
Assoc. Prof. Maria Panopoulou
Courses 2nd Semester
- Biostatistics and Molecular Epidemiology
- Molecular Diagnostics
- International Medicine – Global Health
- Antimicrobial Agents and Resistance
- Immigrant and Tropical Medicine
- Zoonotic Diseases – The ‘One Health’ concept
- Laboratory Courses II
ECTS 5
Coordinators
Assoc. Prof. Ioannis Karakasiliotis
Assoc. Prof. Georgios Boulougouris
Course Layout
SECTION I (2h)
- Global disease control
- European and American disease control centers
- Greek disease control center and legislation
- World health organizations, Reference centers and Reporting
SECTION II (2h)
- Molecular Genetics of Infectious agents
- Informatics tools for molecular genetics
- Phylogenetic trees
- Molecular evolution
SECTION III (2h)
- Molecular typing of bacterial pathogens
- Epidemiology of antibiotics resistance
- Examples of bacterial molecular epidemiology (tuberculosis, helicobacter)
- Evolution of virulence
- Molecular typing of viruses
- Virus evolution and quasispecies
- Examples of viral molecular epidemiology (Influenza, viral hepatitis)
SECTION IV (2h)
- Biostatistics of Infectious diseases
- Introductory Concepts
- Discrete and continuous Probabilities, Characteristic Distributions
- Statistical Inference: Analysis of variance ANOVA, Z and t tests
- Sample size and Power
- Survival Analysis
ECTS 5
Coordinators
Assoc. Prof. Maria Panopoulou
Assoc. Prof. Ioannis Karakasiliotis
Course Layout
SECTION I (4h)
- Introduction to molecular methods
- Current molecular technologies in infectious diseases diagnosis
SECTION II (4h)
- Advanced molecular diagnostic technologies in Infectious Diseases (NGS, microarrays, proteomics…)
SECTION III (4h)
- Current and future molecular diagnostics in Bacteriology
- Troubleshooting
SECTION IV (4h)
- Current and future molecular diagnostics in Virology
ECTS 5
Coordinators
Prof. Konstantinos Mimidis
Asst. Prof. Vassiliki Dalla
Course Layout
SECTION I (4h)
- International Medicine: a scientific discipline or a humanistic necessity
- International Medicine in Greece
- Introduction to International Medicine
SECTION II (4h)
- Global Health
SECTION III (4h)
- NCD-Diabetes as a global health issue
- Infections in Diabetes Mellitus
- Trauma from a global perspective
- Infections related to trauma
SECTION IV (4h)
- Integrated care for tuberculosis
- Global HIV epidemic
- Hepatitis A,B,C,D, E
- Malaria
ECTS 4
Coordinators
Asssoc. Prof. Maria Panopoulou
Asst. Prof. Petros Rafailidis
Course Layout
SECTION I (3h)
- Classification of antimicrobial agents
- Mode of action of antimicrobial agents
SECTION II (5h)
- Molecular mechanisms of antimicrobial resistance
- Antimicrobial stewardship
SECTION III (1h)
- Biofilms
SECTION IV (3h)
- Control and prevention of hospital acquired infections
- Antimicrobial drug development
ECTS 3
Coordinators
Prof. Konstantinos Mimidis
Asst. Prof. Konstantinos Liapis
Course Layout
SECTION I (4h)
- General approach to the patient
- Gastrointestinal Infections in Tropical Medicine
- Respiratory Infections
- Cardiovascular Infections
SECTION II (4h)
- Infections in Haematology
- Infections in Ophtalmology
- Infections in Neurology
- Infections in Nephrology
SECTION III (4h)
- Doctors without boarders-experiences-challenges
- Travel and Infections
- Musculoskeletal Infections in Tropical Medicine
SECTION IV (4h)
- Migration and Tropical Medicine: experiences from the field
- Imaging in Tropical Medicine
- Pathology in Tropical Medicine
ECTS 3
Coordinators
Prof. Katerina Chlichlia
Prof. Anastasia Diakou
Course Layout
SECTION I (2h)
- Zoonotic Diseases and “One Health” concept
- Interplay between human health, animal health and environment
- Most common zoonotic diseases
SECTION I (2h)
- Metazoan Zoonoses
- Trichinosis, Cysticercosis, Hydatid disease
SECTION II (3h)
- Viral Zoonoses
- Rabies, Avian Influenza, Viral hemorrahagic fevers, West-Nile fever, Hepatic E virus infections (HEV), Zika virus infections
SECTION II (1h)
- Prion diseases: spongiform encephalopathies (TSEs)
SECTION III (4h)
- Bacterial Zoonoses
- Anthrax, Brucellosis, Leptospirosis, Listeriosis, Lyme disease, Psittacosis, Q fever, Tularemia, Cat scratch disease, Plague, Rickettsial infections
- Enteric infections: Salmonellosis, Shigellosis, Campylobacter spp, Yersina spp.
SECTION IV (4h)
- Protozoan Zoonoses
- Leishmaniasis, Cryptosporidiosis, Giardiasis, Toxoplasmosis
ECTS 5
Coordinators
Assoc. Prof. Ioannis Karakasiliotis
Asst. Prof. Marianthi Georgitsi
Course Layout
SECTION I (2h)
- Molecular diagnostic techniques
SECTION II (2h)
- Molecular mechanisms of resistance
SECTION III (2h)
- Molecular diagnostic techniques
SECTION IV (2h)
- Molecular diagnostic techniques
The total ECTS credits required to obtain the Master of Science in Infectious Diseases and International Medicine is ninety (90). Students complete 60 ECTS of coursework in semesters A and B. Attendance of lectures and laboratory sessions is mandatory. The dissertation thesis during the final semester (20 ECTS) and the seminars (10 ECTS) will provide students with the opportunity to consolidate and apply the knowledge acquired in coursework.